Additive Benefits of EFAs In Dogs With Atopic Dermatitis After Partial Response To Antihistamine Therapy
S. Paterson
J Small Anim Pract. 1995 Sep;36(9):389-94.
Animal Medical Centre, Chorlton, Manchester
It has been reported that 20 to 70 per cent of atopic cases
in the dog can be controlled with antihistamines, though the effective antihistamine
cannot be predetermined. Combination therapy with essential fatty acids (EFAs)
and antihistamines has been shown to be useful in dogs. All of the work published
to date has been performed in open studies, without the use of placebo, and
in dogs where the aim has been to control pruritus as a symptom rather than
that caused specifically by atopy. The aim of this study was to assess the
combined effects of four antihistamines; hydroxyzine, chlorpheniramine, cyproheptadine
and clemastine; with both an EFA supplement and a placebo of olive oil, in
25 dogs to control pruritus in clinically proven cses of atopy.
Potomac, Maryland 20854