Please look at http://www.dermapet.com to see our many updates, Protocols including the popular TrizEDTA Bacterial Otitis Protocol (Step 6 in the SEVEN Steps to Treating Ears as described in detail in this Newsletter), the Pruritic Clinical Trial, previous Newsletters and articles. THE NEW BROCHURE IS ON LINE.
We are proud to announce that GARY BOUGE, formerly General Manager of IVD, is our Vice President, Sales, effective May 1. We are equally pleased to add JACK WHITE, formerly VP Sales for DVM, based in Texas, as a consultant and in charge of a Regional Territory in the South Central United States.
Please go to http://www.dermapet.com or call 800-755-4738 for purchasing information. You may also contact select distributors such as Burns, Columbus Serum, NLS, MWI, Penn Vet, PVP, Merritt, Premier, R & S Pharma, R. Weinstein (Hawaii), TW Vet Supply, Vet Med Supply and Vetpo. We can now provide you a dominant distributor anywhere you may be in the USA (including Alaska and Hawaii). We are also available in Canada via CENTRAL SALES, Japan, Thailand, Taiwan, Korea, Hong Kong, and Central America and soon in Europe.
EUROPEAN VETS: We are shipping TrizEDTA for $11.99 (per 4 ounce/cases of 12) INCLUDING SHIPPING BY FEDEX.
We will be at Myrtle Beach for the Southeastern Vet Conference June 6-10 where featured speakers include PETER IHRKE and LOU GOTTHELF. Of course, we will be in Boston for the AVMA meeting.
MedRx is offering CE doing their EAR Seminars on the road next in BALTIMORE on July 8 and SEATTLE on July 29. Be there to hear LOU GOTTHELF teach you the latest, state of the art otology. Ears represent the #1 complaint of pet owners to vets (VPI insurance claims, 2000). Call Kenny Keith at 888-392-1234 to register or find out when one is coming near you.
YADA, YADA, YADA
Virtual Reality Misinformation
Many of you may have noticed that for the first time DermaPet is trying to sell products using conventional sales techniques as opposed to strictly on the merits of our products. Credit should go to Gary and Jack for placing these programs in place. Having Gary and Jack around has also afforded us with "ears on the street" with regards to what other companies are saying and doing.
It appears some competitive companies' sales people have located a large population of vets unfamiliar with cyber-jargon. To this unsuspecting group, these unscrupulous sales people are twisting our claim as "the largest vet derm company in virtual reality" saying that, of course, DermaPet is not as big as DVM or Virbac. They then infer that if we are misleading about this then "what can DermaPet be trusted to say?" For the sake of the minority of you who read this Internet only letter, I will define "virtual reality" as "in cyberspace, the internet or the world wide web." To that end, using that definition, DermaPet is clearly the leader in veterinary dermatology in "virtual reality". Consequently, in "reality", we have removed the "cyber-phrase" from as much print advertising as possible and placing "#1 Web Site in Veterinary Dermatology." Please call or email us if you someone has tried to mislead you or a colleague.
"Heard on the Street"
This is a section that we want to relate stories related by practitioners using our products. If requested, your name, practice and location will appear. This months experience is from a practice that sold the DentAcetic to a dentist, although skeptical about other benefits, had a relationship with his pet that became "closer" after using DentAcetic as a "breath freshener."
Ototoxicity /Chlorhexidine
Contrary to rumors well supported by marketers of ototoxic products, there are choices to treat ears that do not involve the use of ototoxic chemicals. This newsletter will discuss one of the worst. It is a fact that chlorhexidine has been shown to cross even intact tympanum and cause permanent pathological otic damage. (Mansfield). It is also a fact that no product containing any active amount of chlorhexidine is labeled or 'publicly' marketed for use in ears.
Companies that label a product as a "Flush" containing chlorhexidine can not place on the label or market to vets either directly or indirectly that product for use in ears. An animal that suffers an adverse reaction using one of these products leaves the owner with the right to claim liability on the part of all selling parties. An overused explanation is that the pet was already suffering from progressive ear problems. Several cases have been reported and have been well demonstrated on the Internet. It is always best to use products that are labeled for the target organ you are attempting to treat.
Ed note: We have received numerous calls and comments from vets about the above paragraph. It is still not well known that chlorhexidine has no place in otic therapy. Please feel free to contact me about your experiences involving any derm or otologic experience, in particular, the use of ototoxic substances.
Readers are encouraged to read Mansfield's article.
Malassezia and Bacterial Otitis PROTOCOLS
While it is true that the acetic/boric acid products have efficacy against Pseudomonas, they are actually FIRST LINE topical treatment while the TrizEDTA (Step 6) remains the best protocol for treatment after the acetic/boric acid is used using Step 3b or Step 4 (See the Seven Steps to Treating Ears under Protocols at http://www.dermapet.com). BOTH OF THESE PRODUCTS CAN BE USED IF THERE IS A RUPTURED TYMPANUM.
The entire text for the SEVEN STEPS to EAR THERAPY is available online.
RECENT RESEARCH by Dr. Louis GOTTHELF and SULIMAN GBADAMOSI (Tuskeghee, Micro Dept) indicate that there is a need to instill TrizEDTA, preferably by a cleaning exercise, before using antibiotics. In fact, when testing samples that were previously reported as resistant to flouroquinolones (using MICs), eight dilutions of our stock TrizEDTA were required to not inhibit growth. This indicates that the TrizEDTA is bactericidal by itself.
Step 6.
1.Orbafloxin (Dicural/Ft Dodge) Marbofloxin (Zenoquin/Pfizer) or Baytril (Bayer) systemically for at least 21-60 days.
>From Lou Gotthelf
For those of you wanting to know how much Baytril to give a patient orally, you need to know the MIC of the organism. The rule of thumb is that you want a tissue level of Baytril to be 8 times the MIC. You can find tissue levels in the package insert for Baytril. Based on the tissue level, you can figure out how many mg/kg you will need to administer to your patient. Are you OK with 5mg/kg or do you need to use 20mg/kg?
Most labs do not give you this information, only if it is sensitive, intermediate, or resistant. If you want to know the endpoint MIC for your intermediate or resistant Pseudomonas, please send the specimen and a check for $12.00 to Dr. Sulaiman Gbadamosi, Tuskegee University, School of Veterinary Medicine, Tuskegee, Alabama 36088. He will do the endpoint MIC for you.
2.Clean with TrizEDTA twice daily.
3.Approximately 15 minutes after each cleaning, instill Baytril (or another appropriate antibiotic (12 ml of saline and 50-200 mg of Baytril injectable) or diluted with saline. Some people use aminoglycosides even though they are ototoxic.
4. For the first 14 days, I would use systemic prednisone at 1 mg/kg IF OM is diagnosed. The rationale is to decrease the inflammation, mucous secretion from the mucoperiosteum, pain and viscosity of the exudate in the tympanic cavity.
5.If OM is diagnosed, I would anesthetize and, with visualization, flush the ear with TrizEDTA and directly instill Baytril and NaDex phosphate into the tympanic bulla. If th tympanum is present and OM is suspected then I would do a myringotomy. The location of the myringotomy should be ventral. Maintenance therapy would include biweekly TrizEDTA cleansing longterm. Some people recommend our acetic/boric acid Ear/Skin Cleanser instead since it has activity against Pseudomonas as well as Malassezia.
Remember: Do NOT be misled by various forms of misinformation as to why certain companies do not use boric acid with acetic acid. The reality is that DermaPet holds a patent on this combination.
SPECIALS
NEW *** BUY 12 DentAcetic and Receive SIX FREE.
Reports from the field indicate Breath Freshening/deodorizing has been a major positive for this new product.
Buy 10 new Laser Wipes and get 2 FREE
Mix and match any of our gallons - Buy 3 get 1 FREE -
Plus Buy 3 cases of any 2 Products and receive a FREE Book, Skin Diseases of Dogs and Cats.
Buy 5 cases of anything and receive the FREE book (one time only) and a FREE Gallon of MalAcetic Shampoo.
DermaPet IS the largest veterinary dermatologic company in virtual reality and the fastest growing. Our Newsletter list, now approaching 12,000 is the largest in the industry with another 7,000 posted indirectly and countless more that read it reposted in newsgroups or lists. Those who receive this newsletter and wish to pass it along to colleagues, please do.
And from out good friends at VIN:
"Don't forget to look for DermaPet as a Featured Company on VIN's Industry Partners Site, an electronic exhibit hall providing 6,000 plus VIN members and all online veterinarians, access to current information from over 900 companies, manufacturers and distributors of the products and services they use daily.
| Steven Melman VMD DermaPet Animal Dermatology and Behavior Clinics Potomac, MD 20854 |
dermapet@aol.com http://www.dermapet.com 800-755-4738 fax 301-365-0191 |
8909 Iverleigh Court 
Potomac, Maryland 20854
301-983-8387 800-755-4738 Fax 301-365-0191
E-mail dermapet@aol.com