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November 2005
Announcing EQUINE Shampoos
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Table of Contents
Evaluating a Boric and Acetic Acid Shampoo
Eicoscaps New Name For OFA Caps Plus EZ-C and Garlic
Territory Managers
Specials
DermaLyte Is the New Name for DermaHypoCs
PetCARE TV Has Formed Alliance With the American Animal
Hospital Association
Release of MalAcetic HC Shampoo, MalAcetic HC Conditioner and MalAcetic HC Wet Wipes
Lou Gotthelf's Small Animal Ear Diseases
Announcing EQUINE Shampoos
DermaPet is pleased to announce our first products specifically designed for
the EQUINE market.
MALACETIC EQ Shampoo is a medicated shampoo useful as a degreaser and in assisting
treatment of most microbial infections including Dermatophilus, scratches and
ringworm using our patented 2% acetic and 2% boric acids. Available only from
veterinarians in a convenient to use 16 oz size.
DERMALLAY EQ uses our cosmetic grade, solubilized oatmeal which is useful as
a general cleanser and for it's anti-inflammatory, anti-pruritic properties.
Available only from veterinarians in a convenient to use 16 oz size.
Evaluating a Boric and Acetic Acid Shampoo
GENE NESBITT, VETERINARY MEDICINE, 10-05, p 726
...conducted an 8 week trial involving 72 dogs with either seasonal or non-seasonal
pruritus. As part of the study, we assessed the effects of an antifungal and
antibacterial shampoo (as well as fatty acid supplementation and antibiotic
and antihistamine administration) in controlling pruritus in dogs. To control
secondary factors contributing to pruritus, all the dogs were bathed weekly
with a commercial shampoo containing 2% acetic acid and 2% boric acid in a soapless
vehicle with moisturizers (MALACETIC Shampoo, DERMAPET). The shampoo contained
no anti-inflammatory agents. We concluded that weekly bathing reduced the Malassezia
species, cocci and aeroallergens on the skin's surface and that this reduction
may have contributed to significant overall improvement in the dog's skin parameter
scores.
Yada, Yada, Yada
Dean's Farewell
Penn, New Bolton Center, Kennett Square
JESSICA and YT attended ALAN KELLY'S farewell party. It seems like only yesterday
when I welcomed him to PENN over a beer or 2 at SMOKEY JOE'S.
I met with classmates MIDGE LEITCH (who I teased tactlessly throughout my vet
school tenure) and NANCY BROWN, with her significant other, BILL KAY, former
AMC guru. The actual class year will be omitted to respect those that have aged
well.
We sat next to WILLIAM J. HARDY, eminent microbiologist who enlightened me
on Bartonella and INFLUENZA, a subject in last month's newsletter. He said Bartonella
was present in over 50% of cats with gingival disease, the cause of Cat Scratch
Fever (a much easier name than the last couple we had to memorize!) and a significant
contributor in feline dermatitis. We became distracted as I wondered about the
association to antibiotic responsive EGC cases.
RENO, Wild West
JACK WHITE, KIM CAREY and YT attended this annual show in Reno. Kim has
made great strides growing the west coast business. BILL TOPLIFF of MedRx joined
us for dinner at the Hilton. While waiting for the show to open and our room
to clear, the craps table was where the action was. DAN ROSSLER rolled 5 4's
bringing new meaning to fourplay; fortunately for me, an "inside player"
(for those who understand craps), he also rolled 4 9's and some 6's and 8's.
And there was leaning going on, too, where old pals ROD ROSYCHUK presented derm
and PETER EMILY (who helped design the DenTees) did dental.
Taj Mahal, ATLANTIC CITY, Atlantic Coast Conference
For those who enjoy gambling around a trade show, like TNAVC coordinator DONNA
GINDY, then October is the month. LOU GOTTHELF slipped in Monday and out Tuesday
to do his otology lecture. GARY LANDSBERG did behavior. JACK WHITE, AL LINGUA,
CHUCK MICHAELS and YT 'worked' this show. Program coordinator, RON WHITFORD,
had top speakers from all over presenting. AVMF'S ROBERT GORDON and SALLY HADDOCK
got their exercise in on the dance floor during the two parties that were hosted
by excellent bands. One of my former students, CURT ARNOLD, from my days as
a derm resident in Illinois, meandered by.
Efficacy and Stability of TrizEDTA Reclarified
The efficacy and stability of TrizEDTA needs to be reclarified. In the study by LOU GOTTHELF and GBADAMOSI (see text below) that was presented at an ACVD/AAVD meeting, Aqueous TrizEDTA needed to be diluted 8x to allow PSEUDOMONAS, previously cultured as resistant to fluoroquinolones, to just grow. Keep in mind that there may be misinformation generated, possibly from a competitor with a potentially ototoxic product containing detergents, alcohol and no USP ingredients. Original work on tris-edta by Wooley et al was using an aqueous product, without further preservative, which has remarkable stability; TrizEDTA has 3 year label dating.
Evaluation of the IN VITRO Effect of TrizEDTA on the Minimum Inhibitory Concentration (MIC) of Enrofloxacin Against Ciprofloxacin Resistant PSEUDOMONAS Aeruginosa. GOTTHELF L and Gbadamosi S (AAVD presentation)
This study examined the in vitro effect of TrizEDTA on the minimum inhibitory
concentration (MIC) of enrofloxacin (ENRO) against 12 strains of ciprofloxacin-resistant
Pseudomonas aeruginosa. The bacterial strains were resistant to ciprofloxacin
(MIC>2 µg/ml, and 5 µg/ml disks). Minimally passaged cultures
of the bacterial strains were grown on nutrient agar, and suspended in 50 mM
tris hydrochloride solution at a concentration equivalent to 0.5 McFarland turbidity
standard, optical density(OD) range of 0.08 to 0.10 according to the National
Committee for Clinical Laboratory Standard (NCCLS) recommendation. To determine
the endpoint MIC, the bacterial suspensions were incubated at 37º C for
30 minutes, and were then transferred into wells of microtiter plates containing
two-fold dilutions of ENRO in Mueller-Hinton broth. Following overnight incubation
at 37º C, wells were examined to determine the endpoint MIC of ENRO against
each bacterial strain. Bacterial cultures were
resistant to ENRO at endpoint MICs ranging from 227 µg/ml to 7.09 µg/ml
The same protocol was repeated after TrizEDTA exposure for 5 minutes at 37º
C. Susceptibility to ENRO MIC decreased to lower than 1.7 µg/ml for all
strains. These observations were further evaluated using 10X bacterial concentrations
with similar results. These findings suggest that TrizEDTA exhibits a sparing
in vitro effect on the MIC of enrofloxacin against ciprofloxacin resistant Pseudomonas
aeruginosa and may benefit treatment of otitis externa infections with both
susceptible and resistant Pseudomonas bacteria.
And, otic products are the #1 reason pet-owners re-visit the vet clinic and/or
visit for an OTC product (Vet Economics).
EICOSACAPS will be the new name for the OFA Caps Plus EZ-C and garlic. This
is our omega 3/6 version very similar to DermCaps except we also have the antioxidants
(Vitamins E and C) plus zinc and garlic.
We are proud to announce KlearWax, a potent cerumenolytic, degreasing, dewaxing product containing Dioctyl Sodium Sulfosuccinate (DSS) and Urea Peroxide. DSS emulsifies wax and debris. Urea Peroxide is a foaming agent to break up larger clumps of debris. This product is recommended for in house cleansing to clear away debris enabling better visualization of the otic canal and TM. It is available in a 4 ounce size in an applicator bottle.
KlearWax is DermaPet's 5th OTOLOGICAL product. They are (1) MalAcetic Otic, (2) MalAcetic Wet Wipes, (3)MalAcetic HC, (4) TrizEDTA and (5)KlearWax. Many people do not realize that DermaPet has global distribution and is now recognized as the market leader in Otology. Plus we have more coming.
Except for the Muller meeting in Hawaii, there are none. Next is the Colonial Meeting in WILLIAMSBURG, December 1-4
MedRx is offering CE
with EAR Seminars by LOU GOTTHELF. They will be in be in ALBANY (11-6), HOUSTON
(11-13) and BIRMINGHAM (12-18).
For more information call 888-392-1234 to find out when one is coming near you.
Al LINGUA will handle the NE from New Jersey north. Al can be reached at 860-810-7280 or ajlingua@aol.com.
KIM CAREY is responsible for the West Coast Kim can be reached at k_carey59@hotmail.com or 916-276-3539.
JAY MAIDEN is our TM for the SE US. Jay can be reached at 727-560-2325 or jaymaiden@verizonmail.com.
COLIN FERGUSON is our Midwest rep. He can be reached at 614-539-9176, cferguso@columbus.rr.com.
The "old work-horse" CHUCK MICHAELS (MidAtlantic TM) and PATRICK RAYBURN (SW TM) ducks2003@cox.net continue to ride with distributor reps.
All our sales are guided by the capable JACK WHITE jag6410@aol.com or call 866-DERMAPET. For the TM nearest you please email, look at our web site or call us.
4th Quarter Specials
Buy 3 totally different (not just a different size of the same product) otic
products and get a 4th unpurchased product free or a case of shampoo. You can
buy any size, but, it must be 3 different products. For example, 1 case of MalAcetic
HC, 1 case of MalAcetic Otic and 1 case of
KlearWax and get 1 case of MalAcetic
Wet Wipes. The least expensive case is FREE. Or instead of the 4 the Otic
add a case of a Shampoo product.
Gallons. Buy 3 and Get 1 FREE.
EicosaDerm is now available in a 32 ounce economy size
Call your DermaPet Distributor or 800 755 4738 for ordering information.
DermaLyte Is the New Name for DermaHypoCs
DermaLyte is the new name for DermaHypoCs.
DermaLyte is our original hypoallergenic shampoo which contains no animal protein,
soap, dyes or fragrances. DermaLyte, available in 8 oz and gallons, is in our
new clear bottles with the purple caps.
PetCARE TV Has Formed Alliance With the American Animal Hospital Association
PetCARE TV has formed an alliance with the American Animal Hospital Association(AAHA)
making a special AAHA version of its popular monthly reception room client education
DVD available to AAHA member hospitals. Also, PetCARE TV will be airing two
new AVMA PSAs titled " Is Your Cat Healthy" and "How Often Does
Your Pet Need A Wellness Exam". These two segments will start appearing
on the December DVD. Lastly, PetCARE TV has arranged for including current pet
news topics from Dr. Jim Humphries Veterinary News Network to be shown on its
monthly DVDs. One of the December topics will be "Disaster Planning with
your pets".
Release of MalAcetic HC Shampoo, MalAcetic HC Conditioner and MalAcetic HC Wet Wipes
Coming soon, we will release MalAcetic HC Shampoo, MalAcetic HC Conditioner and MalAcetic HC Wet Wipes. The Conditioner is a leave-on, dry-on product. All MalAcetic HC products retain their antimicrobial efficacy (See New Treatment of Malassezia Otitis, Gotthelf, Vet Forum, 7/97; Efficacy of an Acetic Acid/Boric Acid Ear Cleaning Solution for Treatment and Prophylaxis of Malassezia sp. Otitis Externa Aust Vet Pract 34[2]:79-82 Jun'04 http://www.dermapet.com/articles/efficacy.pdf and Susceptibility of Selected Otitis Externa Pathogens to Individual and Mixtures of Acetic and Boric Acids, Benson CE, Proc 14th AAVD/ACVD meeting, 1998).
I invite you to read all of the above articles at our web site. In particular, note that MalAcetic is 87% and 88% effective against Malassezia and, at .5% MalAcetic is effective against Staphylococcus while at 1% is effective against Pseudomonas. Note: that the 2% strength provided by our MalAcetic Otic and the rest of the MalAcetic line is what you have been relying upon. Now, for those sensitive, inflamed, pruritic or erythematous cases, you can use a gentler product with hydrocortisone.
Lou Gotthelf's Small Animal Ear Diseases
Lou Gotthelf's Small Animal Ear Diseases 2nd Ed is out. There is a chapter by YT as well as many others. At $59.95 this is a great deal considering all the color photos and the fact that ears represent up to 20% of your business.
DermaPet Vision Statement
To be recognized as the leader in developing new and innovative, all natural
yet highly effective products for the veterinary community.
DermaPet Mission Statement
To contribute to your growth and that of the veterinary industry by providing
excellent, unique, innovative all natural yet highly effective products that
embrace the pet, veterinarian, and client relationship.
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Steve Melman VMD
http://www.dermapet.com
dermapet@aol.com
800-555-4738 US order line
301-983-8387 outside US
301-365-0191 fax
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Archive of Newsletters
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| Steven Melman VMD DermaPet Animal Dermatology and Behavior Clinics Potomac, MD 20854 |
dermapet@aol.com http://www.dermapet.com 800-755-4738 fax 301-365-0191 |
8909 Iverleigh Court 
Potomac, Maryland
20854
301-983-8387 800-755-4738 Fax 301-365-0191
E-mail dermapet@aol.com