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October 2006

Dermatophyte Tx Failures


DermaPet will NEVER send an attachment. Although we are relatively sure we are not infected right now, realistic experience tells us to err on the side of caution, so do not open an email from dermapet@aol.com if there is an attachment.


Table of Contents

Dermatophytosis/ LimePlus Dip

Yada, Yada

Meetings

Territory Managers

Specials

Lou Gotthelf's Small Animal Ear Diseases

New PetCARE DVD

DermaPet Vision Statement

DermaPet Mission Statement


Dermatophytosis/ LimePlus Dip

LimePlus Dip has increased the awareness of the use of Lime sulfur for use as the best, and perhaps, only treatment for Demodex gatoi as well as the topical treatment of choice for dermatophytosis. Still there are many treatment failures as described in this article from Moriello (which appears at our web site).

In my experience, the most common causes of treatment failure are an incorrect diagnosis. This most commonly occurs when clinical signs alone are used to make a diagnosis, underscoring the need to definitively diagnose dermatophytosis based on a positive fungal culture result alone or in addition to a positive result on direct microscopic examination of hairs.

Reinfection

This most commonly occurs when a cat is exposed to a contaminated environment or to other cats with positive culture results, such as those that are sub clinically infected or carriers.
Environmental decontamination is extremely important in the treatment process, not unlike treating the environment in flea infestation cases. And the more animals involved in the outbreak, the greater the environmental contamination.

A contaminated environment. This can cause consistently positive culture results or fluctuations between negative and positive culture results, especially if only a few colonies are present on the fungal culture plate.

Resistant organisms

It is unknown how often resistance occurs. Most of the cases of resistance I have investigated on referral have been related to owner compliance problems; incorrect drug doses; drug intolerance by a cat; the inability to medicate cat; or exposure to carrier cats, contaminated environments, or persistently infected cats. Each of these causes, with the exception of drug intolerance, should be investigated before making changes in antifungal drug therapy. In cases of drug intolerance, consider changing to a divided-dose schedule or a different drug.
Concurrent illness, certain medications, or a defective immune system. Concurrent systemic illnesses are usually more obvious than defective immune systems. Common concurrent illnesses or therapies that can complicate resolution of dermatophytosis include hyperthyroidism, diabetes mellitus, chronic renal failure, neoplasia or chemotherapy, glucocorticoid administration, demodicosis, and infection with feline leukemia or feline immunodeficiency virus.

Refusal to clip medium-haired or longhaired cats or any cat with generalized dermatophytosis. Unfortunately, many owners become convinced of the need to clip their cats' coats only after treatment takes longer than expected or infection persists.

DermaPet is going so far East, it is necessary to go west to get there. YT will be visiting business concerns in KOREA and CHINA. It will be my honor to lecture in SEOUL on 10-22, WUHAN, CHINA at CSAVA on October 29 and BEIJING on November 1. There should be many gems for those who follow the newsletter chronicles and Yada, Yada. Amongst my many objectives will be a search for chinese herbal cures. It is true that while most tourists will be looking at examples of ancient civilization or shopping for souvenirs, YT can be found in local apothecaries and herbal remedy shops. First dog,Roxy, will not be taking this trip, although she certainly would like to and I have no fear of animal right abuses.

Please look at our Compendium listing for DermaBenSs which contains 2.5% BENZOYL PEROXIDE, 1% SULFUR and 1% Salicylic acids. It is the only benzoyl peroxide product containing both sulfur and salicylic acids on the market. Demand for this product has been increasing since a similar product without salicylic acid went on backorder. For the correct listing go to Compendium Listing.

MalAcetic HC Wipes are particularly useful to treat skin fold problems, especially in inflamed areas. The most common of these include breed predispositions such as bulldogs, most spaniels, Bassett’s, Shar pei as well as vulvar, facial, eye, chin, lip and tail folds. Cats with eosinophilic granuloma complex, particularly the eosinophilic ulcer and dogs with “hot spots” aka ‘pyotraumatic dermatitis’ do well on these since they have both antimicrobial as well as anti-inflammatory effects.

Reports are in that TrizEDTA Plus is enjoying growing support as a flushing agent for tracheal washes as well bacterial rhinitis. Experts are adding 1000-1200 mg of aminoglycosides such as amikacin or gentocin to the 4-ounce bottle before flushing. See Antibiotic-tromethamine-EDTA lavage for the treatment of bacterial rhinitis in a dog. | Wooley RE Berman AP | Shotts EB Jr | J Am Vet Med Assoc | 1979 Oct 15 | v. 175 | (8) | p.817-8. Others are using the same mix as a bladder flush for FUS and other resistant cystitis cases.

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Yada, Yada

Jack and PATRICK RAYBURN did the SouthWest Veterinary Symposium in Ft Worth.

Other than that there was very little to talk about.

PATRICK RAYBURN attended the family oriented CE By the Sea program (Port
Aransas, TX) for the 3rd time where over 200 veterinarians attended. <br><br>

Look for our postcard this month from vetdek.com.

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Meetings

We will be at the ACVC in Atlantic City on October 17-19 as well as many regional and state meetings. I will be lecturing on Otology in SEOUL on October 22, in WUHAN at the CHINA Small Animal Veterinary Association (CSAVA) annual meeting on October 29 then BEIJING on October 31.

We have been advised that the Mandalay Bay and The Hotel in Las Vegas have a severe room shortage for Sunday, February 18. In fact, there are no rooms available that night due to the NBA All Star game. My advice is to book your rooms NOW at the Four Seasons and other nearby hotels while you can get them.

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Territory Managers

Territory Managers

Introducing BOB MARSHALL who will handle the Northwest. Bob can be contacted at bob.dermapet@sbcglobal.net, and 916-290-3557.

JEFF SERVE will handle the midwest including Ohio, Michigan and Indiana; Jeff can be reached at serve610@sbcglobal.net and 419-509-2242.

DOTTIE ASMUSSEN, who will handle the Midwest. Dottie lives in Hannibal, MO and can be reached at dottie.asmussen@gmail.com or 573-406-8616.

HARRY STEGALL has the Mid Atlantic States (NC, SC, GA, VA and others). Harry resides in Charlotte and can be reached at 704-577-3830, or dermapet@carolina.rr.com .

ROB CONN handles the southern region of the West Coast. Rob can be reached at 818.585.0632 (Cell) or rob.DermaPet@adelphia.net

Al LINGUA is in the NE from New Jersey north. Al can be reached at 860-810-7280 or ajlingua@aol.com.

JAY MAIDEN is our TM for the SE US (FL MS, AL, TN, KY) . Jay can be reached at 727-560-2325 or jaymaiden@verizonmail.com .

The "old work-horse" CHUCK MICHAELS fencepostcharlie@yahoo.com or 240-447-7248. (Middle eastern US/PA, Ohio, MI, IND, WV etc) and PATRICK RAYBURN (SW TM) ducks2003@cox.net or 817-559-7878, continue to ride with distributor reps.

All our sales are guided by the capable JACK WHITE jag6410@aol.com or call 866-3376 or 866-DERMAPET. For the TM nearest you please email, look at our web site or call us.

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Specials

4th Quarter 15th ANNIVERSARY SALE

All shampoos are buy-one, get one free. Visit 4th Quarter Specials for the details.

Call your DermaPet Distributor or 800 755 4738 for ordering information.

15 years ago, DermaPet was conceived with what is now DermaLyte Shampoo and with a spray-on, leave-on conditioner that has now been improved to DermAllay Conditioner. We started as a hard-working, service oriented company that looked to use natural products to cure every-day derm problems and stayed the course. Private labels supported us for the first 6 years until we became profitable, mainly from our MalAcetic line. We now have a vast array of products in the derm, nutraceutical and dental disciplines in multiple labels sold worldwide. We are known as experts in manufacturing quality products and understanding vet’s needs from the trenches. CHRIS VON STEIN , our COO, has won two awards in the last year for Service and Fulfillment; under his leadership we have avoided all but short back-orders. DAVE BROWN, our CFO, keeps our numbers on track. Industry veteran, JACK WHITE, VP SALES, has built and operates the sales force, maintains distributor relations and guides us with his vast industry experience. Please join us in celebrating our 15th Anniversary this quarter.

While we have just released LIMEPLUS DIP, the industry standard for topical treatment of dermatophytosis, we continue to do research on our MalAcetic line. You will find an expanded version of articles on our web site Our most recent additions are our articles on Dermatophytosis.

MedRx is offering CE with EAR Seminars by LOU GOTTHELF. For more information call 888-392-1234 or visit their web site to find out when one is coming near you.

DENTEES continues to show a substantial increase in market share, of late. We suspect this, in part, may be due to all the press Greenies, who were recently bought by Mars, is receiving. DENTEES are a softer, gentler, more digestible version with acetic acid, HMP for the teeth and gum health, and odofactants for the breath. The term odofactant was coined by PETER EMILY.

MALACETIC Otic AP is a gentler version of MalAcetic Otic. In those rare cases where a pet may react you can now try MalAcetic AP and/or back off from all topicals, and/or try a corticosteroid systemically first and/or dilute the MalAcetic Otic. MALACETIC AP WIPES are now available.

TrizEDTA and TrizEDTA Plus are truly Aqueous products with virtually no propylene glycol or any other surfactants or preservatives. These are stable (3 year shelf life) and effective products with decades of R&D proving their efficacy. See our discussion with WOOLEY in the April 06 newsletter.

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Lou Gotthelf's Small Animal Ear Diseases

Lou Gotthelf's Small Animal Ear Diseases 2nd Ed is out. There is a chapter by YT as well as many others. At $64.95 this is a great deal considering all the color photos and the fact that ears represent up to 20% of your business.

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New PetCARE DVD

PetCARE TV Network is introducing an updated, inexpensive version of its DVD for new pet owners, to be included with "new pet" starter kits, titled "Welcome Home Your New Friend". The objective of the DVD is to educate new pet owners about the behavioral challenges they will likely face with their new pet and the importance of "partnering" with their veterinarian. Contact them at info@petcaretv.com .

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DermaPet Vision Statement
To be recognized as the leader in developing new and innovative, all natural yet highly effective products for the veterinary community.

DermaPet Mission Statement
To contribute to your growth and that of the veterinary industry by providing excellent, unique, innovative all natural yet highly effective products that embrace the pet, veterinarian, and client relationship.

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Check our Protocols, Brochure, MSDS sheets, Newsletter archives and list of Distributors on our web site. Those who receive this newsletter and wish to pass it along to colleagues, please do. Those who wish to be removed from the list please reply "unsubscribe."

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DermaPet IS the largest veterinary dermatological company in "virtual reality"-cyberspace, for those who might otherwise misunderstand the phrase- and the fastest growing. Our Newsletter list, now approaching 18,000, is the largest in the industry with countless more that read it forwarded by colleagues, reposted in newsgroups or lists. Those who receive this newsletter and wish to pass it along to colleagues, please do.

Steve Melman VMD
http://www.dermapet.com
dermapet@aol.com
800-555-4738 US order line
301-983-8387 outside US
301-365-0191 fax

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Archive of Newsletters
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Steven Melman VMD
DermaPet
Animal Dermatology and Behavior Clinics
Potomac, MD 20854
    dermapet@aol.com
http://www.dermapet.com
800-755-4738
fax 301-365-0191

8909 Iverleigh Court Potomac, Maryland 20854
301-983-8387 800-755-4738 Fax 301-365-0191
E-mail dermapet@aol.com

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