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November 2007

Dermatophytosis


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Table of Contents

TrizULTRA+KETO is now available in the new 12 ounce size

Yada Yada

Meetings

Territory Managers

Specials

Technical Bulletins

Lou Gotthelf's Small Animal Ear Diseases

DermaPet Vision Statement

DermaPet Mission Statement


TrizULTRA+KETO is now available in the new 12 ounce size

Mal-A-Ket (1% keto, 2% acetic acid and 2% chlorhexidine) is now in a WET WIPE as well as the new Shampoo.

Dermatophytosis is a serious problem facing veterinarians worldwide. Most cases are seen in domestic cats.

Diagnosis is made by fungal culture, while some do hair and scale examinations, as well, using potassium hydroxide or mineral oil preps. The classic macroconidia known as arthroconidia are not seen in Trichophyton sp but rather in the more common M canis or gypseum. Physical examination revealing fluorescence of hairs is a vastly inferior diagnostic test as it is misread too often. Skin biopsy, when spores are found in the hair follicle is pathognomonic though not seen in all cases.

Cultures maybe obtained by plucking hairs in areas where there are lesions or toothbrush cultures where not. A derm-duet with both dermatophyte media and Sabourauds dextrose agar are best for culture at room temperature. Evaluation for color change and colony formation are done daily over 2-4 weeks.

Topical therapy is important in all cases. It is especially important in very young cases who are too small for accurate systemic dosing and other patients who for various reasons can not undergo proper systemic therapy. The best topical therapy known is lime sulfur (LIMEPLUS DIP, 97.8% sulfurated lime, DermaPet). Other topical therapies that can be done concurrent with lime sulfur are various formulations with ketoconazole (Mal-A-Ket. DermaPet), miconazole, acetic acid (Mal-A-Ket), acetic and boric acids (MalAcetic, DermaPet), terbenafine (Lamisil) and enilconazole. Enilconazole is illegal to use in the US and it is illegal to use an EPA labeled product targeted for use in one species in another species. Lime sulfur is by far the most effective and economical topical therapy. Positive results as a result of topical therapy must be discounted since dermatophytosis may self-cure in some patients.

Systemic therapies used for cats include itraconazole (5-10 mg/kg/qd) first choice for cats), ketoconazole (10 mg/kg/QD) and fluconazole (5 mg/kg/BID in dogs and cats) . Treatment must go on for 2 negative cultures.

Clipping the patient remains controversial. Advantages would be increased efficacy of topical therapy, decreasing future environmental contamination revealing hidden dermatologic manifestation of cutaneous disease (often useful to increase client compliance). Disadvantages include environmental /facility contamination, skin trauma and cosmetics.

Environmental treatments include bleaching (1:10) all contact items. Some people use lime sulfur as well such as when using a carrier or cage to restrain the patient. Professional steam cleaning (to assure properly high water temperatures) of carpets and drapes is recommended.

It is beyond the scope of this presentation to discuss shelters. ALL cats are sprayed with lime sulfur at admission and isolated from the general population. DermaPet is the only supplier of lime sulfur (LIMEPLUS DIP) labeled for use in cats in 1 gallon containers.

Karen Moriello, the person this author respects as the foremost expert on this subject, has written articles further elaborating on dermatophytosis. Readers are suggested to go to
Monitoring Treatment and Preventing Reinfection in Cats with Dermatophytosis and Feline Dermatophytosis: Topical and Systemic Treatment Recommendations.

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Yada, Yada

Barbados, Commonwealth Veterinary Conference

YT opened the meeting with a lecture on 7 Steps to Treating Ears and Topical Therapy. For the next 4 days, the booth was almost totally ignored due to excellent beach and golf conditions. Lou Gotthelf, after ably presenting his Otology lectures and wet lab, and YT played the Barbados CC where, after a grueling match, Lou, with a hustling par on the 18th, eked out the back nince for a consolation, even though YT won the match.

Organized by Barbados resident vet, GUS READER, and his wife, DEBBIE, and their trusty associate, MICHELLE BELL,. the meeting ran seamlessly. There were no delays; despite fears of things slowing down and restless natives in the Caribbean, at least in Barbados all buses, events and programs stayed on schedule to the minute and the attitude was "can-do" with a smile.. BILL TOPLIFF (Medrx) had a good meeting, far exceeding his sales expectations. BOB COHEN (Spectrum Labs) was also quite pleased by the presence of new business. KERSTI SEKSAL (Past Pres, Australia VMA) and DIANE FRANK (Canada) presented Behavior. Animal Planet celebrity HARRY COOPER (Australia) and his wife JEANINE were most entertaining. And, then there was the world's best rum, both Cockspur and Mt Gay. The former gave out all the free VSOR rum during one of the free food and party evenings; the attitude of the crowd was much more exhilarating that night than the next morning. There were people from organized veterinary medicine from all over world notably Africa, India, Australia and the Caribbean. GRAHAM BROWN and CANDACE PHIPPS (Jamaica), TUNJI NASIR (Nigeria), SHARON SHEPARD (Trinidad), COLLIN BOYLE (St Vincent), JOSHUA DeSILVA (Guyana)just to name a few.

And, next year, we hope to see you at the Caribbean Veterinary 25th Biennial Conference November 6-9 in St Martin's.

MAUI, George Muller Derm Conference

JACK WHITE went to Hawaii while YT was in Barbados. Jack reported a good meeting attended by 185 vets including DICK McCARTHY and classmate, ED MOLESWORTH as well as our good friends, TESSY MATSUBARA and KAORU MATSUMOTO from Japan. The meeting was well organized by UC/Davis and laid back -the standard wear was shorts and aloha shirts.

See at our web site "Topical Ketoconazole Antifungal Therapy" by LOU GOTTHELF, VPN, 8/07 (for a complete unedited version go to www.dermapet.com)

Go to KetoFlyer6.pdf

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Meetings

We will be at the:

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Territory Managers

BOB MARSHALL handles the Northwest. Bob can be contacted at bob.dermapet@sbcglobal.net, and 916-290-3557.

DOTTIE ASMUSSEN handles IL, IA, WI, MN, NE, KS, MO, ND, and SD. Dottie lives in Hannibal, MO and can be reached at dottie.asmussen@gmail.com or 573-406-8616.

ROB CONN handles the southern region of the West Coast. Rob can be reached at 818.585.0632 (Cell) or rob.dermapet@sbcglobal.net

Al LINGUA is in the NE from New Jersey north. Al can be reached at 860-810-7280 or ajlingua@aol.com.

JAY MAIDEN is our TM for the SE US (FL MS, AL, TN, KY) . Jay can be reached at 727-560-2325 or jaymaiden@verizonmail.com .

The "old work-horse" CHUCK MICHAELS fencepostcharlie@yahoo.com or 240-447-7248, works the Middle eastern US, PA, WV, DC, MD, VA and DE.

PATRICK RAYBURN (SW TM) ducks2003@suddenlink.net or 817-559-7878, continues to ride with distributor reps.

All our sales are guided by the capable JACK WHITE jag6410@aol.com or call 866-3376 or 866-DERMAPET.

For the TM nearest you please email, look at our web site or call us.

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Specials

4th Quarter 2007 Specials - Buy any 3 cases of shampoo and get a case of TrizUltra+KETO 4oz Free.

Call your DermaPet Distributor or 800 755 4738 for ordering information.

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Technical Bulletins

TECHNICAL BULLETINS are at our web site.

Previously, we showed how our LIME PLUS Dip has 29% more lime sulfur than the new LymDip. The new LymDip is a much weaker formula that has not survived the test of time (neither for efficacy or stability). Despite their citing literature, there is not one refereed publication supporting the use of this substantially diluted product. There also is reason to believe that fragrances used in this product (the addition of which required the dilution from a 97.8% like LimePlus to 76.9% in LymDip) will cause contact irritation/dermatitis.

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Lou Gotthelf's Small Animal Ear Diseases

Lou Gotthelf's Small Animal Ear Diseases 2nd Ed is out. There is a chapter by YT as well as many others. At $64.95 this is a great deal considering all the color photos and the fact that ears represent up to 20% of your business.

MedRx is offering CE with EAR Seminars by LOU GOTTHELF. For more information call 888-392-1234

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DermaPet Vision Statement
To be recognized as the leader in developing new and innovative, all natural yet highly effective products for the veterinary community.

DermaPet Mission Statement
To contribute to your growth and that of the veterinary industry by providing excellent, unique, innovative all natural yet highly effective products that embrace the pet, veterinarian, and client relationship.

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DermaPet IS the largest veterinary dermatological company in "virtual reality"-cyberspace, for those who might otherwise misunderstand the phrase- and the fastest growing. Our Newsletter list, now approaching 18,000, is the largest in the industry with countless more that read it forwarded by colleagues, reposted in newsgroups or lists. Those who receive this newsletter and wish to pass it along to colleagues, please do.

Steve Melman VMD
http://www.dermapet.com
dermapet@aol.com
800-555-4738 US order line
301-983-8387 outside US
301-365-0191 fax

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Archive of Newsletters
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Steven Melman VMD
DermaPet
Animal Dermatology and Behavior Clinics
Potomac, MD 20854
    dermapet@aol.com
http://www.dermapet.com
800-755-4738
fax 301-365-0191

8909 Iverleigh Court Potomac, Maryland 20854
301-983-8387 800-755-4738 Fax 301-365-0191
E-mail dermapet@aol.com

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